Related Experiment Video

Updated: Aug 9, 2026

Single Molecule Fluorescence Microscopy on Planar Supported Bilayers
20:00

Single Molecule Fluorescence Microscopy on Planar Supported Bilayers

Published on: October 31, 2015

[Modeling of tetrodotoxin-sensitive structures of passive transport with planar phospholipid membranes]

Iu V Sokolov, M K Malysheva, V K Lishko

    Biofizika
    |May 1, 1982
    PubMed

    More Related Videos

    Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies07:31

    Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies

    Published on: September 1, 2023

    Lipid-Protein Membrane Structure-Function Characterization using Droplet Interface Bilayers10:27

    Lipid-Protein Membrane Structure-Function Characterization using Droplet Interface Bilayers

    Published on: June 12, 2026

    Related Concept Videos

    Fluid Mosaic Model01:34

    Fluid Mosaic Model

    The fluid mosaic model was first proposed as a visual representation of research observations. The model comprises the composition and dynamics of membranes and serves as a foundation for future membrane-related studies. The model depicts the structure of the plasma membrane with a variety of components, which include phospholipids, proteins, and carbohydrates. These integral molecules are loosely bound, defining the cell’s border and providing fluidity for optimal function.LipidsThe most...
    Membrane Fluidity01:26

    Membrane Fluidity

    Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
    Mosaic nature of the membrane
    The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is a relatively...
    Fluid Mosaic Model01:19

    Fluid Mosaic Model

    Scientists identified the plasma membrane in the 1890s and its principal chemical components (lipids and proteins) by 1915. The model for plasma membrane structure, proposed in 1935 by Hugh Davson and James Danielli, was the first model to be widely accepted in the scientific community. The model was based on the plasma membrane's "railroad track" appearance in early electron micrographs. Davson and Danielli theorized that the plasma membrane's structure resembled a sandwich with the analogy of...
    Asymmetric Lipid Bilayer01:35

    Asymmetric Lipid Bilayer

    Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
    Membrane Asymmetry Regulating Transporters01:19

    Membrane Asymmetry Regulating Transporters

    Enzymes like flippase, floppase, and scramblase transfer phospholipids from one layer to another in the membrane, thereby affecting membrane asymmetry.
    Flippase
    Eukaryotic flippases are type-IV P-type ATPases or P4-ATPases belonging to P-type ATPase family proteins that are membrane-bound pumps involved in the ATP-mediated transport of ions and molecules across the membrane. Flippases flip specific phospholipids from the outer to the inner leaflet of a membrane. All P4-ATPases have one...
    Cellular Membranes and Drug Transport01:24

    Cellular Membranes and Drug Transport

    Drugs must traverse multiple biological barriers, such as multi-layered skin, single-layered intestinal epithelium, and the plasma membrane, to reach their target sites within the body. The plasma membrane, a highly structured composite of phospholipids, carbohydrates, and proteins, is the cell's protective boundary, facilitating selective substance exchange.
    Phospholipids arrange themselves into a bilayer, with hydrophilic heads oriented outward and hydrophobic tails facing inward.