Related Experiment Video
Updated: Jul 30, 2026

08:35
A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
Published on: March 17, 2015
Initiation and inhibition of shivering in the rat: interaction between peripheral and central factors
Clinical and Experimental Pharmacology & Physiology
|January 1, 1982
Abstract:
1. Unanaesthetized, female white laboratory rats were subjected to almost square-wave changes in ambient temperature, from 20 degrees C to 35 degrees C, in a small climatic chamber. 2. Intracerebroventricular injections of serotonin and methysergide were made in shivering, unanaesthetized rats. 3. The integrated electromyogram of m. suprascapularis was recorded as a quantitative measure of shivering activity to monitor the effects of the above procedures. 4. Both warm transients and serotonin inhibited shivering, but methysergide blocked only the effect of serotonin.

