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Computer tomography in transient global amnesia

G Ladurner, A Skvarc, W D Sager

    European Neurology
    |January 1, 1982
    PubMed
    Summary
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    Transient global amnesia (TGA) may be linked to stroke. Computer tomography revealed lesions in some TGA patients, suggesting a potential association with completed strokes.

    Area of Science:

    • Neurology
    • Radiology
    • Neuroimaging

    Background:

    • Transient global amnesia (TGA) is a distinct neurological condition characterized by sudden, temporary memory loss.
    • The underlying pathophysiology and potential association with cerebrovascular events remain areas of investigation.

    Purpose of the Study:

    • To investigate the neuroimaging findings in patients presenting with transient global amnesia (TGA).
    • To determine the prevalence of stroke and other abnormalities on computer tomography (CT) scans in TGA patients.

    Main Methods:

    • Retrospective analysis of computer tomography (CT) scans from 16 patients diagnosed with transient global amnesia (TGA).
    • Evaluation of CT findings for evidence of stroke, atrophy, or other lesions.

    Main Results:

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    • Of 16 TGA patients, CT scans were normal in 7.
    • Atrophy was observed in 2 patients; a single hypodense lesion in 6 patients; and a bilateral lesion in 1 patient.
    • Crucially, all 3 patients with co-occurring amnesic stroke exhibited a hypodense lesion on CT.

    Conclusions:

    • Computer tomography (CT) imaging in transient global amnesia (TGA) can reveal abnormalities, including hypodense lesions.
    • The presence of hypodense lesions on CT in TGA patients may indicate an associated completed stroke.
    • Neuroimaging plays a role in evaluating the potential cerebrovascular underpinnings of TGA.