[Action of enkephalins and their analogs on gastric secretion]

The gastric secretion induced by histamine increased under the influence of enkephalin analog Tyr--D--Ala--Gly--Phe(NO2)NH2. The enkephalin analog Tyr--Gly--Gly--Phe--Leu--D--Arg increased the amount of gastric juice and pepsin, but the debit of hydrochloric acid was lower than in perfusion of histamine alone. Another analog of enkephalin Tyr--D--Ala--Gly--Phe--D--Leu--Arg administered together with histamine decreased the gastric juice secretion only within 90--105 min after the beginning of the perfusion.