Benign neural invasion in vasitis nodosa

Three instances of invasion of nerves of the spermatic cord by benign proliferative ductules of the vas deferens following vasectomy are reported. This phenomenon occurred in association with the histopathological features of vasitis nodosa and was noted in tissue removed during vasovasostomy in two cases and from a painful lower inguinal nodule at the site of vasectomy in a third example. Such neural invasion deserves attention because, especially in association with a proliferative ductular pattern, it may be mistaken for adenocarcinoma. The lesion is also of intrinsic interest in the light of benign neural invasion at other sites.