Liquid membrane phenomena in haloperidol action

Haloperidol, a surface-active neuroleptic drug, was shown to generate a liquid membrane on a supporting membrane. Transport of adrenalin, noradrenalin, dopamine, serotonin, histamine, glutamic acid, gamma-aminobutyric acid, and sodium, potassium, and calcium ions through the haloperidol liquid membrane was studied. The data indicate that the phenomenon of a liquid membrane plays a significant role in the mechanism of action of haloperidol.