[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role

Subchronic treatment with phencyclidine in adolescence leads to impaired exploratory behavior in adult rats without altering social interaction or N-methyl-D-aspartate receptor binding levels.

Journal of neuroscience research·2014

Agonist-induced desensitization of 5-HT(2) receptors on cultured calf aortic smooth muscle cells.

Neurochemistry international·2009

Effects of lesions on (3)H-apomorphine and (3)H-spiperone stereospecific binding sites in subcellular fractions of rat striatum.

Neurochemistry international·2009

Synthesis and biodistribution of [11C]R107474, a new radiolabeled alpha2-adrenoceptor antagonist.

Bioorganic & medicinal chemistry·2006

Bilateral control of brain activity by dopamine D1 receptors: evidence from induction patterns of regulator of G protein signaling 2 and c-fos mRNA in D1-challenged hemiparkinsonian rats.

Neuroscience·2005

Synthesis and biodistribution of [(11)C]R116301, a promising PET ligand for central NK(1) receptors.

Bioorganic & medicinal chemistry·2005

Mechanism of activity inversion for GluN2B-selective negative allosteric modulators.

Molecular pharmacology·2026

A conserved conformation-dependent mechanism for the TREK two-pore domain potassium channel inhibitors carvedilol and fluphenazine.

Molecular pharmacology·2026

High potency μ-opioid receptor agonists engage sodium-bound receptor states.

Molecular pharmacology·2026

Regulation of transient receptor potential ankyrin-1 agonist-induced airway epithelial cell injury and repair by protein kinase C and p38 mitogen-activated kinase.

Molecular pharmacology·2026

The molecular geography of cell signaling diseases.

Molecular pharmacology·2026

Promotion of tumor cell senescence by the antibody-drug conjugate, sacituzumab govitecan.

Molecular pharmacology·2026

Gaussian accelerated molecular dynamics simulations reveal inhibitor-dependent loop dynamics in aminopeptidase N.

Journal of molecular graphics & modelling·2026

Neutral sphingomyelinase 2 inhibitors based on the imidazo[1,2-b]pyridazin-3-amine scaffold.

Bioorganic & medicinal chemistry·2026

The precursor paradox for monoterpene biosynthesis in angiosperms.

Planta·2026

Functional and Mechanistic Characterization of SARS-CoV-2 NSP15 Reveals Metal-Dependent Regulation and Inhibition by Direct-Binding Small Molecules.

The Biochemical journal·2026

Chemical reactions for the ligand-directed modification of native proteins.

Chemical Society reviews·2026

Cyclase-generated 3',5'-cGMP activates PucsarTIR antiphage defense through a stepwise zig-zag aligned filament assembly.

bioRxiv : the preprint server for biology·2026

Related Experiment Videos

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain

Related Concept Videos

Subchronic treatment with phencyclidine in adolescence leads to impaired exploratory behavior in adult rats without altering social interaction or N-methyl-D-aspartate receptor binding levels.

Agonist-induced desensitization of 5-HT(2) receptors on cultured calf aortic smooth muscle cells.

Effects of lesions on (3)H-apomorphine and (3)H-spiperone stereospecific binding sites in subcellular fractions of rat striatum.

Synthesis and biodistribution of [11C]R107474, a new radiolabeled alpha2-adrenoceptor antagonist.

Bilateral control of brain activity by dopamine D1 receptors: evidence from induction patterns of regulator of G protein signaling 2 and c-fos mRNA in D1-challenged hemiparkinsonian rats.

Synthesis and biodistribution of [(11)C]R116301, a promising PET ligand for central NK(1) receptors.

Mechanism of activity inversion for GluN2B-selective negative allosteric modulators.

A conserved conformation-dependent mechanism for the TREK two-pore domain potassium channel inhibitors carvedilol and fluphenazine.

High potency μ-opioid receptor agonists engage sodium-bound receptor states.

Regulation of transient receptor potential ankyrin-1 agonist-induced airway epithelial cell injury and repair by protein kinase C and p38 mitogen-activated kinase.

The molecular geography of cell signaling diseases.

Promotion of tumor cell senescence by the antibody-drug conjugate, sacituzumab govitecan.

Gaussian accelerated molecular dynamics simulations reveal inhibitor-dependent loop dynamics in aminopeptidase N.

Neutral sphingomyelinase 2 inhibitors based on the imidazo[1,2-b]pyridazin-3-amine scaffold.

The precursor paradox for monoterpene biosynthesis in angiosperms.

Functional and Mechanistic Characterization of SARS-CoV-2 NSP15 Reveals Metal-Dependent Regulation and Inhibition by Direct-Binding Small Molecules.

Chemical reactions for the ligand-directed modification of native proteins.

Cyclase-generated 3',5'-cGMP activates PucsarTIR antiphage defense through a stepwise zig-zag aligned filament assembly.

Related Experiment Videos

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain...

Related Concept Videos

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[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain