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Acute sterile peritonitis

B E Alpert, V W Folkert, R E Longnecker

    Nephron
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    A new condition, acute sterile peritonitis (ASP), presents during peritoneal dialysis with sudden pain and fever. This aseptic peritonitis resolves quickly with continued dialysis and features cloudy dialysate but negative cultures.

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    Area of Science:

    • Nephrology
    • Internal Medicine
    • Clinical Syndromes

    Background:

    • Peritoneal dialysis is a common treatment for end-stage renal disease.
    • Aseptic complications can arise during peritoneal dialysis, necessitating careful monitoring.
    • Understanding novel syndromes is crucial for effective patient management.

    Observation:

    • A previously undescribed sporadic syndrome, termed acute sterile peritonitis (ASP), has been identified.
    • ASP occurs in 0.1% of peritoneal dialysis sessions.
    • Symptoms include abrupt onset of abdominal pain, fever, chills, and vomiting during dialysis.

    Findings:

    • Dialysate return becomes cloudy with elevated white blood cell counts.
    • Microbiological cultures of the dialysate are consistently negative.

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  • Symptoms resolve spontaneously within hours with continued dialysis.

    • Implications:

    • ASP represents a distinct clinical entity requiring recognition.
    • This syndrome highlights the need for differential diagnosis in dialysis-related abdominal symptoms.
    • Further research into the pathogenesis and management of ASP is warranted.