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Updated: Aug 13, 2026

The Mouse Hindbrain As a Model for Studying Embryonic Neurogenesis
Published on: January 29, 2018
Neocytes and neocyte-gerocyte exchange
Abstract:
Patients requiring chronic transfusions deposit large quantities of iron throughout their reticuloendothelial and parenchymal systems. Diabetes mellitus, hepatic fibrosis, and cardiomyopathy are the ultimate pathologic manifestations. One mechanism for decreasing the rate of iron loading would be to transfuse only the youngest cohort of cells from a donor (neocytes). At the same time the patient's oldest red cells are being removed (neocyte-gerocyte exchange). In this manuscript we describe techniques presently available for such a procedure.
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