Radionuclide brain imaging--its role and relation to CT scanning

Separate CNS disease entities are discussed with either the complementary or exclusive indications for radionuclide brain imaging and computerized cranial tomography. Either modality alone has a potential overall precision somewhat in excess of 90% in the localization of cerebral lesions with the effectiveness of each modality differing according to the histology and anatomic location of the lesion. Most investigators agree that the combined application of the two procedures is far superior to their separate use. Routine dynamic isotope studies are essential and in addition, new radiopharmaceuticals and technological advances may improve the radionuclide evaluation of CNS disease. Areas discussed include: primary and secondary CNS neoplasms; acute cerebrovascular accidents; arteriovenous malformations; traumatic cerebrovascular disease; hydrocephalus and dementia; and intracranial inflammatory processes.