[Hypophyseal-adrenal system function in disseminated breast cancer]

The functional condition of the pituitary-adrenal system was studied in 94 patients with disseminated breast cancer. A decreased excretion of 17--OCS's with urine and an increased cortisol level in blood were observed. This was interpreted as relative (extra-adrenal) failure of pituitary-adrenal function in breast cancer patients. Measures of long-term therapy (adaptogens, vitamins and hepatotropic preparations) are recommended.