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Convulsive syncope in blood donors

J T Lin, D K Ziegler, C W Lai

    Annals of Neurology
    |May 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Convulsive syncope, a rare event in blood donors (0.03%), can mimic seizures. Individual susceptibility to central nervous system ischemia may predispose some donors to these reactions.

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    Area of Science:

    • Neurology
    • Cardiology
    • Hematology

    Background:

    • Syncope is a common cause of fainting.
    • Convulsive syncope is a rare variant.
    • Blood donation is a common setting for vasovagal reactions.

    Purpose of the Study:

    • To investigate the incidence and characteristics of convulsive syncope in blood donors.
    • To compare convulsive and non-convulsive syncope in this population.

    Main Methods:

    • Observational study of unselected blood donors.
    • Data collection on syncope events, including convulsive episodes.
    • Comparison of physiological parameters between groups.

    Main Results:

    • Convulsive syncope occurred in 0.03% of blood donors.

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  • It was more frequent when personnel were alerted and in men.
  • No significant differences in pulse or blood pressure changes were noted between convulsive and non-convulsive syncope.
  • Individual susceptibility to cerebral ischemia varies, potentially predisposing to seizures during hypotension and bradycardia.

    • Conclusions:

    • Convulsive syncope in blood donors is infrequent but can present with complex movements resembling seizures.
    • Physiological responses do not differentiate convulsive from non-convulsive syncope.
    • Central nervous system susceptibility to ischemia is a key factor in seizure development during hypotensive events.