A modified cows' milk formula suitable for low birthweight infants

Area of Science:

• Neonatal Nutrition
• Pediatric Gastroenterology

Background:

• Low birthweight infants require high fluid intake for nutrition, increasing risks.
• Preterm infants are susceptible to late hyponatremia due to renal sodium losses.

Purpose of the Study:

• To evaluate a new concentrated cow's milk formula (Prematalac) for low birthweight infants.
• To compare its safety and efficacy against a standard formula regarding fluid and sodium balance.

Main Methods:

• Ten low birthweight infants received Prematalac (150 ml/kg/day).
• Twelve similar infants received standard formula (180 ml/kg/day).
• Growth, clinical course, and electrolyte balance were monitored.

Main Results:

• Both groups exhibited intrauterine growth rates with no clinical differences.
• Prematalac group avoided hypernatremia, edema, and dehydration.
• No infants in either group developed hyponatremia.

Conclusions:

• Prematalac facilitates adequate nutrition with reduced fluid volume in low birthweight infants.
• The new formula supports safe excretion of osmotic load and higher urinary sodium.
• Prematalac may offer protection against late hyponatremia in preterm infants.