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Related Experiment Videos

Motor lateralization in manic males

H A Nasrallah, M McCalley-Whitters

    The British Journal of Psychiatry : the Journal of Mental Science
    |May 1, 1982
    PubMed
    Summary

    Handedness in male patients with mania was studied. Unlike schizophrenia, mania does not appear to be linked to increased left or mixed-handedness.

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    Area of Science:

    • Neuroscience
    • Psychiatry
    • Human Biology

    Background:

    • Handedness, the preferential use of one hand over the other, is a complex trait.
    • Previous research has indicated an association between non-right-handedness (left- or mixed-handedness) and certain neurological and psychiatric conditions, notably schizophrenia.
    • The relationship between handedness and bipolar disorder, specifically mania, remains less understood.

    Purpose of the Study:

    • To investigate whether male patients experiencing mania exhibit a different pattern of handedness compared to male control subjects.
    • To determine if mania shares the association with non-right-handedness observed in other psychiatric disorders like schizophrenia.

    Main Methods:

    • A handedness test was administered to assess lateral preference.
    • The study included 88 male patients diagnosed with mania.
    • A control group of 86 healthy male subjects was recruited for comparison.

    Main Results:

    • No statistically significant difference in handedness was found between the manic patient group and the control group.
    • Both groups exhibited similar distributions of right-handedness, left-handedness, and mixed-handedness.

    Conclusions:

    • The findings suggest that mania, in contrast to schizophrenia, is not associated with an increased prevalence of left- or mixed-handedness.
    • This indicates that the neurobiological underpinnings of mania may differ from those of schizophrenia concerning lateralization and handedness patterns.

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