Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Variant forms of angina pectoris

W A van Ekelen, E O Robles de Medina

    European Journal of Cardiology
    |October 1, 1978
    PubMed
    Summary

    Coronary artery spasm presents a wider clinical spectrum than previously known, affecting patients at rest and during exercise. Manifestations vary, impacting myocardial ischemia severity and diagnosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The relationship between electrocardiographic abnormalities and location of the intracranial aneurysm in subarachnoid hemorrhage.

    Pacing and clinical electrophysiology : PACE·2003
    Same author

    Early outcome after off-pump versus on-pump coronary bypass surgery: results from a randomized study.

    Circulation·2001
    Same author

    Exercise performance in patients with end-stage heart failure after implantation of a left ventricular assist device and after heart transplantation: an outlook for permanent assisting?

    Journal of the American College of Cardiology·2001
    Same author

    Increased dispersion and shortened refractoriness caused by verapamil in chronic atrial fibrillation.

    Journal of the American College of Cardiology·2001
    Same author

    The Octopus Study: rationale and design of two randomized trials on medical effectiveness, safety, and cost-effectiveness of bypass surgery on the beating heart.

    Controlled clinical trials·2001
    Same author

    Reduction of radiation exposure in the cardiac electrophysiology laboratory.

    Pacing and clinical electrophysiology : PACE·2001

    Area of Science:

    • Cardiology
    • Vascular Medicine

    Background:

    • Coronary artery spasm, a condition causing temporary narrowing of coronary arteries, can lead to myocardial ischemia.
    • Prinzmetal's original description focused on specific clinical and electrocardiographic patterns.

    Observation:

    • Three patients with coronary artery spasm exhibited diverse clinical and electrocardiographic presentations.
    • Anginal attacks occurred at rest in all patients; two also experienced exercise-induced angina without significant fixed coronary narrowing.
    • Electrocardiogram (ECG) findings during pain included ST-segment elevation, ST-segment depression, or a combination.

    Findings:

    • Coronary angiography confirmed spontaneous or induced spasm in all three patients.
    • Sublingual nitroglycerin (NTG) provided incomplete relief in two cases, questioning the interpretation of residual stenosis.
    • The study demonstrates a broader clinical spectrum of coronary artery spasm than previously reported.

    Implications:

    • Clinical and ECG manifestations of coronary artery spasm are likely influenced by the spasm's location and severity.
    • These variations can lead to different degrees of myocardial ischemia.
    • Diagnostic approaches may need to consider the wide variability in spasm presentation.

    Related Experiment Videos