Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Do all diuretics have equal hypotensive efficacy?

G Jaffe, J J Grimshaw, J Gay

    Current Medical Research and Opinion
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Association of Glycemic Gap with In-Hospital Adverse Outcome after First Attack of Acute ST Elevation Myocardial Infarction in Thrombolysed Patients.

    Mymensingh medical journal : MMJ·2025
    Same author

    Designer circRNA<sub>GFP</sub> reduces GFP-abundance in Arabidopsis protoplasts in a sequence-specific manner, independent of RNAi pathways.

    Plant cell reports·2025
    Same author

    Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh.

    Virology journal·2024
    Same author

    Real-Life Management of Patients Aged 80 Years Old and Over With Multiple Myeloma: Results of the EMMY Cohort.

    Clinical lymphoma, myeloma & leukemia·2024
    Same author

    Effects of oyster mushroom (Pleurotus ostreatus) stem residue supplementation on growth performance, meat quality and health status of broilers.

    Poultry science·2024
    Same author

    Evaluation of Antimicrobial Efficacy and Clinical Outcomes of Triphala and 2.5% Sodium Hypochlorite as Intraradicular Irrigants in Pulpectomy of Primary Teeth.

    Mymensingh medical journal : MMJ·2024
    Same journal

    Multidrug-resistant <i>Pseudomonas aeruginosa</i> in Jordan: epidemiology, trends, determinants, and clinical outcomes.

    Current medical research and opinion·2026
    Same journal

    RSV disease and vaccination knowledge, attitudes, and practices among US adults: a 2024-2025 RSV season survey.

    Current medical research and opinion·2026
    Same journal

    Clinical and healthcare resource utilization outcomes following revision knee arthroplasty with and without a gradually reducing radius revision knee system.

    Current medical research and opinion·2026
    Same journal

    Medication adherence measurement methods and their reported relationship with medication safety outcomes: a scoping review.

    Current medical research and opinion·2026
    Same journal

    BMI response to dapagliflozin with or without semaglutide across obesity classes: a real-world observational study conducted in Saudi Arabia.

    Current medical research and opinion·2026
    Same journal

    Comparative efficacy of tislelizumab + FOLFOX or CAPOX for gastric/gastroesophageal junction adenocarcinoma: an exploratory matching-adjusted indirect comparison.

    Current medical research and opinion·2026
    See all related articles

    Hydrochlorothiazide/amiloride demonstrated superior blood pressure reduction and control in mild to moderate hypertension compared to cyclopenthiazide/potassium. This combination therapy offers better patient compliance due to fewer required tablets.

    Area of Science:

    • Cardiology
    • Pharmacology

    Background:

    • Hypertension is a prevalent cardiovascular risk factor.
    • Effective antihypertensive medications are crucial for patient management.

    Purpose of the Study:

    • To compare the efficacy of hydrochlorothiazide/amiloride versus cyclopenthiazide/potassium in treating uncomplicated mild to moderate hypertension.

    Main Methods:

    • An open, parallel study involving 70 patients with hypertension.
    • Randomized treatment with either hydrochlorothiazide/amiloride or cyclopenthiazide/potassium.
    • Dosage titration based on supine diastolic blood pressure targets.

    Main Results:

    • Hydrochlorothiazide/amiloride achieved a greater decrease and better control of blood pressure in more patients.

    Related Experiment Videos

  • The combination therapy required fewer tablets for optimal effect, enhancing patient compliance.

    • Conclusions:

    • Hydrochlorothiazide/amiloride is a more effective treatment for mild to moderate hypertension than cyclopenthiazide/potassium.
    • Improved efficacy and patient compliance make this combination a valuable therapeutic option.