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[Phototoxic reaction to figs]

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    Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
    |June 1, 1982
    PubMed
    Summary

    Fresh fig juice can cause phototoxic reactions, leading to striped or patchy skin pigmentation. This furocoumarin-induced reaction is similar to other plant-based photodermatitis and PUVA therapy.

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    Area of Science:

    • Dermatology
    • Photobiology
    • Toxicology

    Context:

    • Ficus carica (fig) juice contains furocoumarins, which can induce phototoxic reactions.
    • Observed cases include striped pigmentation on arms and patchy facial pigmentation.
    • These reactions occur after sun exposure following topical application or ingestion of fresh figs.

    Purpose:

    • To describe the phototoxic effects of fresh fig juice on human skin.
    • To establish the pathogenetic link between ficus dermatitis and other furocoumarin-induced photodermatoses.
    • To highlight the similarity to Berloque dermatitis, bullous meadow dermatitis, and PUVA therapy.

    Summary:

    • Fresh fig (Ficus carica) juice can cause phytophotodermatitis, presenting as striped or patchy skin pigmentation.
    • The reaction is attributed to furocoumarins in the fig juice, activated by sunlight.
    • This condition shares pathogenetic mechanisms with photodermatitis from citrus oils (Berloque dermatitis) and Heracleum species (bullous meadow dermatitis).

    Impact:

    • Highlights a common yet often unrecognized cause of phytophotodermatitis.
    • Emphasizes the importance of identifying furocoumarin-containing plants in diagnosing photodermatitis.
    • Provides a comparative understanding of furocoumarin-induced skin reactions, aiding in clinical diagnosis and management.

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