[Isoenzymes after physical loading in ischemic heart disease]

The enzyme and isoenzyme pattern was investigated in the plasma of patients with ischaemic heart disease (IHD) after exercise (bicycle test). In comparison to the "exercise profile"and "cardiac profile" differences exist between the characteristic changes of IHD patients. IHD patients with severe impairment of the left ventricle showed a changed enzyme pattern after exercise. The LDH-H-activity and the ratio LDH-H/LDH-M were increased between 1.5 and 8 hours after the exercise. The initially increased LDH-H/LDH-M ratio decreased to normal levels about 24 hours after exercise. The isoenzyme pattern after exercise is discussed in relation to the results of complete heart catheterisation.