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[Asymptomatic microhematuria]

T Cappellini, A Guerra, F Canonaco

    La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

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    Microscopic hematuria in children is often linked to respiratory infections or genitourinary issues. While some cases resolve, younger children (<6 years) show poorer outcomes, unlike older children (>6 years).

    Area of Science:

    • Pediatric Nephrology
    • Urology
    • Immunology

    Background:

    • Microscopic hematuria is a common urinary finding in children, presenting diagnostic challenges.
    • The Addis count is used to quantify red blood cells (RBCs) per minute in urine.

    Purpose of the Study:

    • To investigate the causes and outcomes of microscopic hematuria in pediatric patients.
    • To establish diagnostic criteria and identify prognostic factors for microscopic hematuria.

    Main Methods:

    • A 5-year study (1975-1980) of 123 children with microscopic hematuria, followed for 1-8 years.
    • Utilized Addis counts, clinical data, biological and immunological tests, urography, and renal biopsies for diagnosis.
    • Patients were grouped based on RBC counts and age (<6 vs. >6 years) for follow-up analysis.

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    Main Results:

    • 55% of cases had RBC counts ≤5,000/min, considered normal.
    • Upper respiratory tract infections were found in 65.8% of cases; genitourinary infections in 26%.
    • Renal biopsies revealed mesangial proliferative glomerulonephritis in 5.6% of total cases; 69.6% had minimal changes.
    • Children >6 years showed significant improvement/normalization (p<0.001), while those <6 years showed worsening (p<0.005).

    Conclusions:

    • Microscopic hematuria in children often stems from infections, with a significant portion remaining unexplained.
    • Age is a critical factor in prognosis, with older children experiencing better outcomes.
    • Renal biopsy is valuable for diagnosing glomerulonephritis in selected cases.