Blood pressure drop as a result of fluorescein injection

Our experience with intravenous fluorescein involved 38 administrations in 29 patients. In all, 24 percent were associated with a drop in blood pressure of 20 mmHg or more and 8 percent with a blood pressure fall of 60 mmHg or more. We believe that physicians using fluorescein in bolus form should be aware of the problem of blood pressure reduction and be prepared to take restorative measures when necessary.