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Endobronchial metastatic disease

M P Shepherd

    Thorax
    |May 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Pulmonary metastatic disease diagnosis was established in 28% of patients via bronchial biopsy. Endobronchial metastases, often from primary cancers like breast or colon, were identified, with some cases amenable to surgical resection.

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    Area of Science:

    • Thoracic Surgery
    • Oncology
    • Pulmonary Medicine

    Background:

    • Pulmonary metastatic disease presents a diagnostic challenge.
    • Endobronchial metastases are a rare manifestation of advanced cancer.

    Purpose of the Study:

    • To analyze the incidence and characteristics of endobronchial metastases.
    • To evaluate diagnostic methods and treatment outcomes for pulmonary metastases.

    Main Methods:

    • Retrospective review of 90 patients with pulmonary metastatic disease.
    • Diagnosis confirmed by bronchial biopsy in 25 cases (28%).
    • Analysis of primary cancer sites, time to metastasis, and treatment interventions.

    Main Results:

    • Twenty-four patients had endobronchial metastatic carcinoma; one had sarcoma.

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  • Primary sites included large intestine, breast, cervix, uterus, bladder, and melanoma.
  • Pulmonary metastases were resectable in 10 patients, with long-term survival in some.
  • Interval between primary treatment and metastasis ranged from months to 17 years.

    • Conclusions:

    • Bronchial biopsy is a valuable tool for diagnosing endobronchial metastases.
    • Surgical resection can offer long-term survival for select patients with pulmonary metastases.
    • Endobronchial metastases signify advanced disease, necessitating careful management.