[Treatment of diabetic angiopathy with pentoxifylline]

The therapeutic effect of pentoxyphilin substance--Trental, was followed up in 102 diabetics (35 females and 67 males) aged from 34 to 79 via a broad complex of clinical and paraclinical methods. Favourable results were found in 90.4 per cent of the treated; excellent effect--in 42.3 per cent of the treated; very good--in 22.4 per cent and good--in 28.3 per cent; only 9,6 per cent of the total number with a short-term treatment (average of 27 days) failed to respond with a sufficient effect. Pentoxyphilin is very well tolerated by the patients, not deteriorating the carbohydrate metabolism; has a high effect coefficient upon the diabetic macroangiopathy; that concerns all stages of arterial lesions in the lower limbs. As regards microangiopathy our experience is still poor, thus making definite conclusions is rather risky, in spite of the encouraging results so far. The preparation is worthy of being widely applied in the clinical practice both in the treatment and prophylaxis of diabetic macroangiopathy.