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Dialytic ascitic ultrafiltration in refractory ascites
The American Journal of Gastroenterology
|September 1, 1982
Summary
Dialytic ascitic ultrafiltration offers a new approach for managing refractory ascites in hepatic cirrhosis patients. This procedure safely removes fluid, showing potential for improved patient outcomes.
Area of Science:
- Nephrology
- Gastroenterology
- Internal Medicine
Background:
- Hepatic cirrhosis frequently leads to refractory ascites, a challenging clinical condition.
- Current management options for refractory ascites have limitations and can lead to complications.
Purpose of the Study:
- To evaluate the safety and efficacy of dialytic ascitic ultrafiltration with intraperitoneal reinfusion for refractory ascites.
Main Methods:
- Nine patients with hepatic cirrhosis and refractory ascites underwent the procedure.
- Ascites was removed via a peritoneal catheter and ultrafiltered using a hemodialyzer.
- Concentrated ascites was continuously returned to the peritoneal space.
Main Results:
- A mean of 4.8 liters of protein-free ascitic ultrafiltrate was removed per patient.
- The procedure was well-tolerated, with no adverse effects reported.
- The duration of the procedure ranged from 3 to 5 hours.
Conclusions:
- Dialytic ascitic ultrafiltration is a potentially safe and effective method for managing refractory ascites.
- This technique may offer a valuable new therapeutic option for patients with advanced liver disease.