Related Experiment Video
Updated: Aug 24, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Team approach in providing clinical pharmacokinetic services
Abstract:
A team approach to clinical pharmacokinetic services at a university hospital is described. The clinical pharmacokinetics team (CPT) developed as an outgrowth of a clinical pharmacokinetic service (CPS) as the workload of the service expanded. The CPT serves to: (1) maximize the quality and continuity of clinical pharmacokinetic care; (2) provide a teaching medium for students at the baccalaureate and graduate level; and (3) stimulate the development of clinical pharmacokinetic research. The CPT is responsible for patients in those medical services that are not regularly served by a clinical pharmacist. The structure of the CPT includes an attending clinical pharmacist with a hierarchy of subordinate practitioners ranked by their individual didactic and clinical experience in pharmacokinetics. Students participate in (1) work rounds, where collective discussions of patient evaluations occur, and (2) one-to-one student-preceptor clinical assessments of patients' drug therapy. The attending clinical pharmacist conducts CPT rounds daily, and the students and residents must convey information to the team on: (1) the drug therapy prescribed and the appropriate monitoring methods, (2) the working diagnosis and plan of treatment, (3) results of laboratory and clinical assessments, and (4) details of patient interviews. The CPT is also responsible for ongoing clinical pharmacokinetic research. The team approach to clinical pharmacokinetic services has provided a framework for the education of clinical pharmacists while stimulating research and providing direct patient care.
More Related Videos
10:17High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
07:40Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis
Published on: March 20, 2021
Related Concept Videos
Analysis of Population Pharmacokinetic Data
Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches
The model approach uses mathematical models to describe changes in drug concentration over time. Pharmacokinetic models help characterize drug behavior in patients, predict drug concentration in the body fluids, calculate optimum dosage regimens, and evaluate the risk of toxicity. However, ensuring that the model fits the experimental data accurately...
Model Approaches for Pharmacokinetic Data: Compartment Models
Two primary types of compartment models are recognized: mammillary and catenary. The more...
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Dosage Regimens: Partial Pharmacokinetic Parameters
Pharmacokinetic–Pharmacodynamic Relationship: Problems