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Pancreatitis associated with primary hyperparathyroidism

D Paloyan, D Simonowitz, E Paloyan

    The American Surgeon
    |August 1, 1982
    PubMed
    Summary
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    The incidence of pancreatitis associated with primary hyperparathyroidism has decreased. Earlier diagnosis of parathyroid disease, due to screening, may explain this trend in pancreatitis cases.

    Area of Science:

    • Endocrinology
    • Gastroenterology

    Background:

    • Primary hyperparathyroidism is a condition that can have various clinical manifestations.
    • Pancreatitis has been observed as a complication of primary hyperparathyroidism.

    Purpose of the Study:

    • To review the incidence of pancreatitis in patients with primary hyperparathyroidism.
    • To investigate trends in the association between primary hyperparathyroidism and pancreatitis over time.

    Main Methods:

    • Retrospective review of two patient series treated for primary hyperparathyroidism.
    • Analysis of documented cases of pancreatitis in relation to primary hyperparathyroidism diagnosis.

    Main Results:

    • In an earlier series of 150 patients, six (4%) had pancreatitis associated with primary hyperparathyroidism.

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  • In a more recent series of 26 patients, no cases of pancreatitis were identified.
  • A decreasing trend in pancreatitis incidence among primary hyperparathyroidism patients was observed.

    • Conclusions:

    • The association between primary hyperparathyroidism and pancreatitis appears to be diminishing.
    • Earlier diagnosis of primary hyperparathyroidism, likely due to improved screening methods, may be contributing to the reduced incidence of associated pancreatitis.