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Pathogenesis of vocal cord polyps
The Annals of Otology, Rhinology, and Laryngology
|July 1, 1982
Summary
Vocal cord polyps, unique to the larynx, develop from phonotrauma due to intensive voice use. Investigations reveal altered blood vessel permeability and reactive processes leading to polyp formation.
Area of Science:
- Laryngology
- Pathology
- Voice Science
Background:
- Vocal cord polyps are distinct lesions found exclusively in the larynx.
- They present in various forms, including gelatinous, telangiectatic, and transitional types.
Purpose of the Study:
- To investigate the histopathological basis of vocal cord polyp development.
- To elucidate the role of vascular changes and reactive processes in polyp formation.
Main Methods:
- Histological, histochemical, and electron microscopic examination of vocal cord polyps.
- Analysis of cellular and extracellular matrix components.
Main Results:
- Alterations in blood vessel permeability were observed, leading to extravasation of fluid, fibrin, and erythrocytes.
- Reactive processes resulted in the formation of complex vascular spaces, resembling thrombus organization.
Conclusions:
- Vocal cord polyps are considered a sequela of phonotrauma, particularly in individuals with intensive voice usage.
- The development involves vascular leakage and subsequent reactive vascular proliferation.