[Bureau-Barrière's acro-neuropathy. Complementary studies and definition of ante-acropathy status (author's transl)]

Systematic study of 28 patients suffering of Bureau-Barrière's acro-neuropathy. This study emphasize several particular factors. Significant increase of IgA, with a slight extend of transferrin. The authors debate the straight correction between increase of IgA and nervous illness. Study of peripheral nerves exhibits, in optic and electronic microscopies, direct and indirect signs of wallerian degeneration and significant axonal lesional prevalence. The study of anatomical specimen (foot) corroborates this data. Bony scintigraphic show the constancy of fixation and his connection with bearing surface. Witness demonstrate the specific character of this data. This investigations prove that the Bureau-Barrière's diseases is an alcoholic neuro-acropathy and allow the definition of ante-acropathic status (axonal sensitive neuropathy-scintigraphic fixations, increase of IgA). Prophylaxis in emphasized.