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Coronary artery spasm with sinus node dysfunction and syncope

T T Bashour, O Hakim, A L Ennis

Archives of Internal Medicine

|September 1, 1982

Summary

This summary is machine-generated.

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Coronary artery spasm can cause sinus node dysfunction, leading to dizziness and syncope. Severe, widespread coronary spasm, even in healthy arteries, can be fatal, highlighting its significant cardiovascular impact.

Area of Science:

Cardiology
Vascular Medicine
Electrophysiology

Background:

Spontaneous angina, dizziness, and syncope are concerning symptoms.
Sinus node dysfunction can manifest with these symptoms.
Coronary artery spasm is a potential cause of cardiac events.

Observation:

A 55-year-old male presented with angina, dizziness, and syncope.
Holter monitoring revealed sinus node dysfunction.
Coronary angiography demonstrated severe, diffuse coronary artery spasm.

Findings:

Pacemaker implantation corrected the patient's symptoms.
The patient experienced fatal pump failure post-catheterization.
Autopsy showed minimal coronary atherosclerosis, indicating spasm as the primary issue.

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Implications:

Coronary artery spasm can precipitate sinus node dysfunction and syncope.
Extensive coronary spasm can lead to fatal outcomes.
Severe coronary spasm can occur independently of significant coronary atherosclerosis.