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[Morphological studies of the regulatory mechanisms of intracerebral blood circulation]
Insights
This study investigated the neural and vascular structures within the brain
Area of Science:
- Neuroanatomy
- Cerebrovascular Research
- Histology
Context:
- The intricate neural and vascular networks within the brain are crucial for maintaining local cerebral circulation.
- Understanding the innervation of cerebral arteries is essential for comprehending blood flow regulation.
Purpose:
- To investigate the presence and distribution of neural elements, including sensitive neural terminals, cholinergic plexuses, and adrenergic networks, within the intracerebral arteries.
- To identify monoaminocytes associated with cerebral vessels.
- To explore the potential role of these neurovascular structures in regulating local cerebral blood flow.
Summary:
- Neural and adrenergic networks, along with monoaminocytes, were identified in the walls of intracerebral arteries across various brain regions (parietal, occipital, temporal lobes, tectum mesencephali, pons).
- Sensitive neural terminals and cholinergic plexuses were observed in arteries up to 100 micrometers in diameter.
- Adrenergic networks were found in arteries up to 100 micrometers, and monoaminocytes were present near vessels and within arterial walls.
Impact:
- This research suggests that the intrinsic neural and vascular components of the intracerebral circulatory system play a significant role in regulating local cerebral blood flow.
- Findings contribute to a deeper understanding of neurovascular coupling and may inform future research on neurological disorders affecting cerebral circulation.
Abstract:
The intracerebral branches of the posterior and medial cerebral arteries in the area of the grey and white substances of the parietal, occipital and temporal cerebral lobes, of the nuclei in the superior and inferior colliculi in the tectum mesencephali. as well as in the pons have been studied in 36 male corpses at the age of 5--49 years by means of Cajal, Koelle, Furness and Costa methods. Presence of sensitive neural terminals, cholinergic plexuses has been stated in the intracerebral artery walls with the diameter up to 100 mcm and more, as well as adrenergic neural network on the arteries with the diameter up to 100 mcm and more, as well as adrenergic neural network on the arteries with the diameter up to 40 mcm and more. Besides, near the cerebral substance vessels monoaminocytes situating both in the area of the sphincter torus and in the arterial walls have been revealed. A suggestion is made that the proper neural and other apparatuses of the intracerebral circulatory bed play a certain role in regulation of the local cerebral circulation.