[Correlation between local cerebral blood flow and EEG in experimental cerebral ischemia]

Varying degrees of cerebral ischemia were produced in adult Wistar rats by clipping of bilateral common carotid arteries with or without induced hypotension. Local cerebral blood flow was measured from bilateral caudate nuclei and parietal cortices using the hydrogen clearance method. EEG was recorded from the same electrode as used for the hydrogen clearance method. The delta power of EEG increased along with decreasing local cerebral blood flow. There was an inverse correlation between the delta power of EEG and local CBF values, ranging from normal to extremely low (10 ml/100 g/min). When local CBF was reduced below 6-8 ml/100 g/min, EEG became isoelectric. Continuous EEG recording might contribute to predict rCBF value in the ischemic lesion.