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Macular coccidioidomycosis

L Lamer, F Paquin, G Lorange

    Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
    |June 1, 1982
    PubMed
    Summary
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    Ocular coccidioidomycosis, a fungal infection, presented as a macular lesion in a Canadian patient. Prompt treatment led to rapid healing, suggesting this is the first reported case in Canada.

    Area of Science:

    • Ophthalmology
    • Mycology
    • Infectious Diseases

    Background:

    • Macular lesions can have diverse etiologies, necessitating accurate diagnosis.
    • Fungal infections, such as coccidioidomycosis, can manifest in ocular tissues.
    • Distinguishing ocular coccidioidomycosis from other macular diseases is crucial for appropriate management.

    Observation:

    • A 26-year-old woman presented with an enlarging, dense macular lesion in her right eye.
    • Funduscopic and angiographic findings were atypical for macular histoplasmosis.
    • A concurrent diagnosis of a pulmonary coccidioidomycotic granuloma was established.

    Findings:

    • The patient received treatment with amphotericin B for the pulmonary infection.
    • The macular lesion showed cicatricial changes within one month of treatment initiation.

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  • This case represents presumed ocular coccidioidomycosis, the first reported instance in Canada.

    • Implications:

    • This case highlights the potential for coccidioidomycosis to present with unusual ocular manifestations.
    • Early diagnosis and systemic antifungal treatment can lead to favorable visual outcomes.
    • Increased awareness is needed among clinicians in non-endemic regions for diagnosing ocular fungal infections.