Autopsy findings in squamous-cell carcinoma of the esophagus

The findings at autopsy of 79 patients with esophageal carcinoma over a period of 15 years were reviewed. Five patients were free of tumor, and another seven had disease localized to the esophagus and other mediastinal structures. Sixty-seven (85%) had metastatic disease. The average number of metastatic sites per patient was 3.3. Most common metastatic sites were lymph nodes (73%), lung (52%), and liver (47%). The patients in this series had a higher incidence of metastases than those in other published series. Possible reasons for this discrepancy include race and sex differences between this population and those in previous reports, as well as the fact that this series includes very few postoperative deaths.