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Comparative prolactin profiles in IUD users and non-IUD users
Contraception
|June 1, 1982
Summary
Copper T IUD use did not significantly alter daily human prolactin (hPRL) levels, despite users showing slightly lower average hPRL during the menstrual cycle. Further research is needed to confirm these findings.
Area of Science:
- Reproductive Endocrinology
- Hormonal Contraception
Background:
- Intrauterine Devices (IUDs) are a common form of contraception.
- Hormonal fluctuations, including prolactin levels, play a role in the menstrual cycle.
Purpose of the Study:
- To investigate the relationship between Copper T IUD use and daily serum prolactin (hPRL) levels.
- To compare hPRL patterns in IUD users versus non-users throughout the menstrual cycle.
Main Methods:
- Daily blood samples were collected from 14 Copper T IUD users and 10 controls.
- Serum samples were analyzed using radioimmunoassay (RIA) for hPRL and hLH.
- Statistical analysis was performed on hPRL values.
Main Results:
- Episodic patterns of hPRL secretion were observed in all participants.
- IUD users exhibited generally lower daily hPRL levels compared to controls.
- The observed differences in hPRL levels between IUD users and controls were not statistically significant.
Conclusions:
- Copper T IUD use does not appear to significantly impact daily serum prolactin levels.
- Further investigation may be warranted to explore subtle hormonal differences or long-term effects.
Keywords:
BiologyContraceptionContraceptive Methods--side effectsEndocrine SystemExaminations And DiagnosesFamily PlanningHormonesIud, Copper ReleasingIud--side effectsLaboratory Examinations And DiagnosesLaboratory ProceduresMenstrual CycleMenstruationPhysiologyPituitary HormonesProlactin--analysisReproductionSize