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Dialysis, depression and antidepressants

E A Haffke, S Rajendran, J D Egan

    The Journal of Clinical Psychiatry
    |October 1, 1978
    PubMed
    Summary
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    This study explored depression treatment for patients on chronic renal dialysis. Imipramine was used effectively in the standard dosage for patients requiring antidepressants during dialysis.

    Area of Science:

    • Nephrology
    • Psychiatry

    Background:

    • Depression is a common comorbidity in patients with chronic kidney disease (CKD).
    • Patients undergoing maintenance hemodialysis (MHD) face unique challenges that can exacerbate depressive symptoms.

    Observation:

    • This study observed 22 patients undergoing maintenance hemodialysis.
    • The Dialysis Unit utilized 10 Travenol dialyzers of the recycling single by-pass type.

    Findings:

    • Imipramine was administered to patients experiencing depression during chronic renal dialysis.
    • The standard dosage and schedule of imipramine were employed, showing potential efficacy in this patient population.

    Implications:

    • This research highlights the importance of addressing depression in dialysis patients.

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  • Further investigation into psychotropic medication management for end-stage renal disease (ESRD) patients is warranted.