Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Are spermicides teratogenic?

J L Mills, E E Harley, G F Reed

    JAMA
    |November 5, 1982
    PubMed
    Summary
    This summary is machine-generated.

    This study found no increased risk of birth defects in infants whose mothers used spermicides. Spermicide exposure during pregnancy was not linked to congenital malformations in offspring.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Placental characteristics and risks of maternal mortality 50 years after delivery.

    Placenta·2021
    Same author

    Delayed conception in women with low-urinary iodine concentrations: a population-based prospective cohort study.

    Human reproduction (Oxford, England)·2018
    Same author

    Genome-wide studies of von Willebrand factor propeptide identify loci contributing to variation in propeptide levels and von Willebrand factor clearance.

    Journal of thrombosis and haemostasis : JTH·2016
    Same author

    Performance of prognostic markers in the prediction of wound healing or amputation among patients with foot ulcers in diabetes: a systematic review.

    Diabetes/metabolism research and reviews·2015
    Same author

    Effectiveness of bedside investigations to diagnose peripheral artery disease among people with diabetes mellitus: a systematic review.

    Diabetes/metabolism research and reviews·2015
    Same author

    Effectiveness of revascularization of the ulcerated foot in patients with diabetes and peripheral artery disease: a systematic review.

    Diabetes/metabolism research and reviews·2015
    Same journal

    Online Prescribing of GLP-1 Receptor Agonists.

    JAMA·2026
    Same journal

    Using AI Disagreement to Expose Gaps in Coverage Rules.

    JAMA·2026
    Same journal

    Randomized Trials in Pregnancy.

    JAMA·2026
    Same journal

    Randomized Trials in Pregnancy-Reply.

    JAMA·2026
    Same journal

    WHO Issues Guidelines for Treating Ebola and Marburg Viruses.

    JAMA·2026
    Same journal

    FDA Approves Additional Naloxone Nasal Spray for Opioid Overdose.

    JAMA·2026
    See all related articles

    Area of Science:

    • Reproductive Health
    • Teratology
    • Obstetrics

    Background:

    • Emerging evidence suggested spermicides might pose teratogenic risks.
    • Understanding the safety of contraceptive methods during pregnancy is crucial.

    Purpose of the Study:

    • To investigate the association between maternal spermicide use and congenital malformations in offspring.
    • To determine if spermicide exposure increases the risk of birth defects.

    Main Methods:

    • Prospective study involving pregnant women reporting contraceptive use.
    • Data collection on spermicide and other contraceptive exposures prior to and during early pregnancy.
    • Offspring malformation assessment via medical record abstraction.

    Main Results:

    Related Experiment Videos

    • No increased malformation rate observed in offspring of spermicide users compared to other contraceptive users.
    • Analysis by organ system and specific defects showed no spermicide-associated risk.
    • Controlling for confounding factors did not alter the findings.

    Conclusions:

    • Maternal spermicide exposure before or after the last menstrual period is not associated with an increased risk of congenital malformations.
    • Current evidence does not support a link between spermicide use and birth defects.