Five-year follow-up of oestrogen therapy in 94 women

The present paper reviews a cohort of peri- and post-menopausal women who commenced hormone therapy in 1975 with follow-up observations for 5 yr. The study indicates that more than half of the patients discontinued treatment for various reasons within the 5 yr period. The drop-out rate was proportionately much greater in the bone clinic patients than in the menopause clinic patients. The reasons for this are discussed.