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Related Experiment Videos

Evaluation of brainstem stroke using brainstem auditory evoked responses

B J Stern, A Krumholz, H D Weiss

    Stroke
    |September 1, 1982
    PubMed
    Summary

    Brainstem auditory evoked responses (BAERs) can help predict outcomes in stroke patients. Abnormal BAERs in brainstem stroke cases often indicate an unstable clinical course and poorer prognosis.

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    Area of Science:

    • Neurology
    • Neurophysiology

    Background:

    • Brainstem stroke diagnosis relies heavily on clinical criteria.
    • Limited diagnostic tools exist for evaluating brainstem ischemic events.
    • Brainstem auditory evoked responses (BAERs) offer a novel electrophysiologic method for assessing brainstem function.

    Purpose of the Study:

    • To evaluate the utility of BAERs in diagnosing and predicting outcomes for patients with brainstem ischemic events.
    • To correlate BAER results with clinical course and lesion location in brainstem stroke patients.

    Main Methods:

    • Thirty-five patients with recent brainstem strokes, confirmed by strict clinical criteria, underwent BAER evaluation.
    • BAER results were analyzed in conjunction with clinical course (stable vs. unstable) and lesion site (mesencephalic, pontine, medullary).

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    Main Results:

    • Initial BAERs were abnormal in 63% of patients.
    • An abnormal BAER was significantly associated with an unstable clinical course (79% of unstable patients vs. 44% of stable patients, p=0.04).
    • Pontomesencephalic infarction with abnormal BAERs indicated a particularly poor prognosis, with 8 of 9 deaths occurring in this subgroup.

    Conclusions:

    • Abnormal BAERs in brainstem stroke patients correlate with an unstable clinical course.
    • BAERs may serve as a valuable prognostic tool in the early assessment of brainstem ischemic strokes.
    • Pontomesencephalic lesions with abnormal BAERs portend a grave prognosis.