[Modern detergents and their application in pediatrics]

Area of Science:

• Dermatology
• Toxicology
• Cosmetic Science

Context:

• Widespread use of chemical products, particularly detergents, has raised concerns about potential adverse effects on human skin.
• Over 100 million people daily encounter surface-active substances, necessitating an understanding of their impact on skin physiology.
• Previous research has explored the effects of detergents on the skin's protective mechanisms and overall health.

Purpose:

• To review the literature on the effects of detergents on human skin over the past decade.
• To assess the safety and tolerance of anion-active detergents for general and pediatric use.
• To identify conditions and factors influencing skin reactions to detergents.

Summary:

• Anion-active detergents generally show good skin tolerance, with injuries primarily occurring under extreme conditions like pre-existing skin damage or constitutional anomalies.
• Children aged 6-12 years exhibit similar resistance to acids and alkalis as adults, though the buffering capacity development in newborns requires further investigation.
• Modern detergents are recommended for pediatric hygiene, especially for infants, provided they are selected based on individual skin type and condition.

Impact:

• Provides evidence-based recommendations for the safe use of detergents in pediatric populations.
• Highlights the importance of personalized skincare approaches when using detergent products.
• Contributes to the understanding of skin barrier function and its interaction with common chemical agents.