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Amniotic band syndrome

J W Seeds, R C Cefalo, W N Herbert

    American Journal of Obstetrics and Gynecology
    |October 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Amniotic band syndrome causes fetal malformations due to fibrous bands. Early diagnosis and genetic counseling are crucial for affected infants.

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    Area of Science:

    • Medical Genetics
    • Developmental Biology
    • Obstetrics

    Background:

    • Amniotic band syndrome (ABS) is a spectrum of congenital anomalies.
    • It involves fibrous bands entrapping fetal parts in utero, causing deformities.
    • ABS presents a consistent clinical pattern despite varied nomenclature.

    Purpose of the Study:

    • To review the clinical features, epidemiology, and diagnostic status of ABS.
    • To summarize and illustrate the range of malformations associated with ABS.
    • To examine major etiological theories and recommend clinical management.

    Main Methods:

    • Literature review of clinical features, epidemiology, and diagnosis.
    • Summary and illustration of malformation spectrum.
    • Examination of etiological theories.

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    Main Results:

    • ABS is characterized by fetal malformations from amniotic bands.
    • Misdiagnosis and inadequate counseling are common issues.
    • A wide spectrum of malformations can occur.

    Conclusions:

    • Accurate diagnosis and genetic counseling are vital for ABS cases.
    • Specialized consultation is recommended for infants with ABS features.
    • Understanding the etiology and clinical spectrum aids management.