Electrophoretic types of leucine aminopeptidase in sheep serum

Leucine aminopeptidase in sheep serum was studied by starch gel electrophoresis. Two phenotypes, A and B, were observed, of which the former was present in 70-90% of all the sheep examined. These two phenotypes have been shown to be controlled by a single autosomal locus, with two alleles LapA and LapB. The LapA allele is dominant. The frequencies of Lap phenotypes and alleles were determined in eleven Spanish and two foreign breeds. Serum alkaline phosphatase and serum leucine aminopeptidase are electrophoretically distinct.