In vitro evaluation of U.S. and U.S.S.R. artificial hearts

Area of Science:

• Biomedical Engineering
• Cardiovascular Research
• Medical Device Evaluation

Background:

• In vitro evaluations are crucial for assessing artificial heart devices.
• Standardized testing procedures are needed to compare different artificial ventricle designs.
• Hemolysis, durability, and reliability are key characteristics for artificial heart evaluation.

Purpose of the Study:

• To summarize in vitro evaluation results of Soviet and American artificial hearts.
• To standardize testing procedures for comparing artificial ventricles.
• To evaluate characteristics like hemolysis, durability, and reliability.

Main Methods:

• In vitro testing of artificial hearts from the U.S.S.R. and U.S.A.
• Standardized static and dynamic tests were performed.
• Variations in preload, afterload, rate, and systolic/diastolic intervals were applied.

Main Results:

• All tested artificial heart designs demonstrated comparable function curves.
• The devices proved capable of taking over the pressure and volume work of the natural heart.
• Standardized procedures allowed for direct comparison of different artificial ventricle designs.

Conclusions:

• Soviet and American artificial hearts exhibit comparable in vitro performance.
• Standardized testing facilitates the evaluation and comparison of artificial heart technologies.
• These findings support the potential of artificial hearts to assume natural cardiac functions.