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[Initial evaluations on the use of passive microhemagglutination test for the verification of antitetanus immunity]
First results obtained in the L.P.I.P. of Milan for tetanus antitoxin titration in the serum of 200 subjects vaccinated, are exposed in this work. A micromethod of passive haemoagglutination against avian erythrocytes was employed. The 26.5% of these subjects presents less than 0.1 Ul/ml. of antitoxin in spite of previous immunization. On the contrary in 33% of cases, high levels of antibodies have been determinated in spite of a not correctly executed vaccination. It seems confirmed the validity of this diagnostic procedure for monitoring the prophylaxis against tetanus among the National Sanitary Service and for its more correct management. The study of the results permits in addition to better determine the cases in which this test is suitable.
First results obtained in the L.P.I.P. of Milan for tetanus antitoxin titration in the serum of 200 subjects vaccinated, are exposed in this work. A micromethod of passive haemoagglutination against avian erythrocytes was employed. The 26.5% of these subjects presents less than 0.1 Ul/ml. of antitoxin in spite of previous immunization. On the contrary in 33% of cases, high levels of antibodies have been determinated in spite of a not correctly executed vaccination. It seems confirmed the validity of this diagnostic procedure for monitoring the prophylaxis against tetanus among the National Sanitary Service and for its more correct management. The study of the results permits in addition to better determine the cases in which this test is suitable.