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Interactions between tryptophan and multilamellar liposomes. Effect of n-butanol on tryptophan fluorescence
Abstract:
The fluorescence of indole ring of tryptophan is sensitive to the characteristics of the solvent in which it is located. So that is can be used as a probe of its microenvironment. In the present report we have studied fluorescence changes of tryptophan molecule located in multilamellar liposome of dipalmitoyl-lecithin (DPL). The temperature dependence of tryptophan fluorescence intensity shows increase related to the phase changes in DPL-liposomes. n-Butanol, a fluidizing agent, induces a linear dependence of tryptophan fluorescence from temperature.