Related Experiment Video
Updated: Aug 11, 2026

Cryogenic Sample Loading into a Magic Angle Spinning Nuclear Magnetic Resonance Spectrometer that Preserves Cellular Viability
Published on: September 1, 2020
[Reaction of cells to hypertonic effects by cryoprotection]
Abstract:
Kinetics of volume changes in cells caused by hypertonic solutions has been investigated theoretically using an apparatus of the non-equilibrium thermodynamics. Analytical expressions for relaxation times of the two-stage process studied have been found. The reaction of mouse peritoneal exudate cells to hypertonic solutions of glycerol. PEO-400 or PEO-1500 has been studied experimentally. An agreement has been obtained between theoretical calculations and experimental results. Possible mechanism of cell injury caused by hypertony is discussed.
Related Concept Videos
Tonicity in Plants
Tonicity in Plants
Tonicity
Tonicity describes the capacity of a cell to lose or gain water depending on the solute...
Tissue Homogenization and Cell Lysis
Mechanical methods of tissue homogenization
These methods rely on applying external physical force to disrupt...
Tonicity in Animals
Cellular Injury I: Introduction
Cellular Injury V: Apoptosis and Autophagy

