[Insulin-dependent cytoplasmic regulator activity in the rat liver and heart in fasting and muscle work]

Upon starving and muscle work the activity of an insulin-dependent cytoplasmic regulator (IDR) in the rat liver has been demonstrated to be lowered. This is one of the mechanisms of glycogenolysis and gluconeogenesis stimulation. Rapid increase in IDR activity in the heart and liver has been recorded in the period of recovery after swimming, with the increase being more intense in the heart. It has been shown that in the heart the resynthesis of glycogen proceeds more rapidly than in the liver. Therefore, the rate of glycogen resynthesis by the liver and heart correlates with IDR activity.