Intramedullary ganglioneuroma of spinal cord: a clinicopathologic study

A case of intramedullary ganglioneuroma, a rare tumor occurring in the cervical spinal cord, is presented, and its histologic and ultrastructural features are discussed. In view of the benign course of ganglioneuroma, as represented in this case, it is important to distinguish this tumor histologically from ganglioglioma, a tumor that is histologically similar but has greater malignant potential. The inherent problems in this distinction are discussed. The embryogenesis of ganglioneuroma of the nervous system is also reviewed.