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Related Experiment Videos

Regional left ventricular ejection fraction from real-time two-dimensional echocardiography

A J Rein, D Sapoznikov, N Lewis

    International Journal of Cardiology
    |January 1, 1982
    PubMed
    Summary

    Two-dimensional echocardiography effectively assesses regional left ventricular function. This non-invasive technique quantifies ejection fraction, revealing abnormalities in coronary artery disease and congestive cardiomyopathy.

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    Area of Science:

    • Cardiology
    • Medical Imaging
    • Echocardiography

    Background:

    • Assessing regional left ventricular (LV) function is crucial for diagnosing and managing heart conditions.
    • Traditional methods may be invasive or lack detailed regional analysis.
    • Two-dimensional echocardiography offers a potential non-invasive solution for evaluating LV contraction patterns.

    Purpose of the Study:

    • To evaluate the utility of real-time two-dimensional echocardiography in assessing regional left ventricular contraction patterns and ejection fraction.
    • To compare regional ventricular function in normal subjects, patients with coronary artery disease, and patients with congestive cardiomyopathy.

    Main Methods:

    • Real-time two-dimensional echocardiograms were acquired from 8 normal subjects, 11 patients with coronary artery disease, and 2 with congestive cardiomyopathy.

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  • The left ventricle was divided into 12 regions.
  • Regional ejection fraction was calculated using a geometric method integrating incremental volumes of hemicylinders within each region.

    • Main Results:

    • Normal subjects exhibited uniform regional ventricular patterns with ejection fractions ranging from 54-74%.
    • Patients with coronary artery disease showed varying degrees of regional contraction abnormalities.
    • Patients with congestive cardiomyopathy presented with global hypokinesis and reduced regional ejection fraction (11-39% in all areas).

    Conclusions:

    • Two-dimensional echocardiography is a valuable non-invasive bedside tool for assessing regional left ventricular function.
    • The technique provides detailed quantitative information on regional left ventricular contraction abnormalities.
    • This method aids in differentiating cardiac conditions based on specific patterns of ventricular dysfunction.