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Related Experiment Videos

Hepatobiliary rickets

M E Holda, J R Ryan

    Journal of Pediatric Orthopedics
    |August 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Rickets secondary to liver disease is rare but causes skeletal issues like bone deformities and fractures. This study found 17% of children with chronic liver disease showed signs of rickets.

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    Area of Science:

    • Pediatrics
    • Hepatology
    • Orthopedics

    Background:

    • Rickets secondary to hepatobiliary disease presents skeletal manifestations similar to nutritional rickets.
    • These include epiphyseal plate abnormalities, pseudofractures, bone bowing, scoliosis, and fractures.

    Purpose of the Study:

    • To determine the prevalence of rickets in children with chronic hepatobiliary disease.
    • To describe the skeletal manifestations and orthopedic management considerations.

    Main Methods:

    • Retrospective review of 112 patient charts and radiographs.
    • Analysis of patients with chronic hepatobiliary disease admitted between 1968 and 1978.

    Main Results:

    • Nineteen patients (17%) demonstrated roentgenographic evidence of rickets.
  • Skeletal changes observed were consistent with those seen in nutritional rickets.

    • Conclusions:

    • Rickets is a notable complication in pediatric chronic hepatobiliary disease.
    • Orthopedic management focuses on fracture treatment and deformity correction in long-term survivors.