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Perforating folliculitis and psoriasis

J W Patterson, G E Graff, S W Eubanks

    Journal of the American Academy of Dermatology
    |September 1, 1982
    PubMed
    Summary
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    This study reports a rare case of coexisting psoriasis and perforating folliculitis. Topical retinoic acid showed efficacy in resolving some lesions, suggesting a potential treatment avenue.

    Area of Science:

    • Dermatology
    • Dermatopathology

    Background:

    • Psoriasis is a chronic inflammatory skin condition.
    • Perforating folliculitis is a rare disorder characterized by transepidermal elimination of follicular contents.

    Observation:

    • A 51-year-old male patient with a decade-long history of psoriasis presented with perforating folliculitis.
    • Multiple perforating lesions were observed within existing psoriatic plaques.

    Findings:

    • This represents the second documented case of coexisting psoriasis and perforating folliculitis.
    • Topical retinoic acid therapy led to the resolution of several larger perforating lesions.
    • Histological classification of perforating diseases presented diagnostic challenges.

    Implications:

    Related Experiment Videos

    • The case highlights the potential therapeutic role of topical retinoic acid for perforating folliculitis coexisting with psoriasis.
    • Understanding the pathogenesis of perforating disorders in the context of inflammatory skin diseases is crucial.
    • Further research into the mechanisms and treatment of perforating diseases is warranted.