Stability of concentrated aqueous solutions of pralidoxime chloride

Concentrated aqueous solutions of pralidoxime chloride degrade more rapidly than dilute solutions. The rate and degree of degradation is dependent on the initial and final pH as well as the container in which the solution is stored. The effects of glass, metal, plastic, and rubber stoppers on the stability of concentrated and dilute solutions are discussed. The stability and shelf lives of 50% aqueous concentrates at different temperatures were determined.